Macrolide Antibiotics

Macrolide Antibiotics

The Role of Chromatography in Macrolide Antibiotics Classification

You can use macrolide antibiotics, a type of antibacterial/antimicrobial to treat various bacterial infections. But, it can be challenging to classify them because they all have the same structure/properties and are made up of different chemical compositions. Azithromycin, and erythromycin, are a couple of examples of these antibiotics used.

When you use techniques like column chromatography to separate, classify, and purify the macrolide antibiotic particles, there is a greater chance that the end product and output are highly potent and useful. Thus, certain chromatography techniques, such as high-performance liquid chromatography and thin-layer chromatography are widely used in these applications as they can selectively adsorb the various macrolide antibiotic particles according to their size and shape.


This process makes it easier to tell the difference between the various types of macrolide antimicrobial characteristics/properties, and side chains, as well as their lactone ring, that have identical chemical compositions. So, by looking at which macrolide antibiotic adsorbs best in the silica gel column used, we can break them down into different groups.

Using silica gel for this process can help us understand how the various macrolide antibiotic fractions behave and interact with each other in the column and we can also check the purity and fractions obtained at the end.

You should use silica gel to classify macrolide antibiotics for various reasons. We shall see a few of them below. Silica Gel TLC Plates make sure the process is more rigorous and precise when it comes to the classification of the compounds. They make sure the classification is rightly done with no impurities left behind after the process.

Contrary to various traditional methods, using Silica Gel TLC Plates can be an affordable option when it comes to classifying and purifying macrolide antibiotic compounds. The process is also very simplified when you use them instead of other materials as they are easy to use, maintain, and reuse too.

When used to classify the varied compounds from a macrolide antibiotic mixture, there is also an opportunity to discover new ways in which the individual compounds react and connect with each other and together in the mixture. 

By making use of their selective adsorbing techniques, Silica Gel TLC Plates can be optimally used for macrolide antibiotics. You can use different silica varieties for this process effectively.